Unfortunately, pregnant women are not immune from various diseases. Therefore, they often wonder about what to do and how to treat a disease without harm to the baby. This is truly the most important issue faced by the doctors all over the world. But it’s not so easy to find the right solution. One of the medicines that is generally allowed during pregnancy is Ibuprofen. Can Ibuprofen pregnancy take place? Is it safe for the baby?
Ibuprofen: General Properties and Indications for Use
Ibuprofen is a non-steroidal anti-inflammatory drug that has an anti-inflammatory, analgesic and antipyretic effect. It is widely used to treat such ailments as sciatica, adnexitis, bursitis, neuralgia, arthragra, proctitis and others. But most often Ibuprofen is used to relieve headaches, dental and muscle pain. Also, it is able to eliminate some inflammation and symptoms accompanying respiratory diseases.
Forms of Production and Their Use
The drug is available in various forms:
- pills and capsules;
- effervescent tablets;
- rectal suppositories;
According to the instructions, rectal suppositories are used only for the treatment of children.
- ointments and gels for external use.
It is worth remembering that regardless of the form of Ibuprofen, you need to consult a doctor about the advisability of using it.
Despite such a variety of forms of release, the active substance is the same in all of them. This is Ibuprofen. But its amount and auxiliary components can differ.
Contraindications for Ibuprofen Use
Despite the fact that Ibuprofen belongs to the NSAID group, it should still be taken with caution, since it has a number of contraindications for use:
- erosive and ulcerative diseases of the gastrointestinal tract in the active phase;
- violations of the liver and kidneys;
- hypersensitivity to the components of the drug;
- pregnancy (the third trimester);
- the presence of diseases associated with hematosis (anemia caused by various causes, problems with blood coagulability);
- severe heart failure.
Ibuprofen Pregnancy: Classification by FDA
In the United States, Food and Drug Administration (FDA) was established. It issuing international certificates of the product safety standard to pharmacological companies. In addition, the FDA developed a scale of effects on the fetus of those medications that were taken by women during pregnancy. All drugs can be divided into 6 categories (A, B, C, D, X, N), depending on the research conducted and the degree of risk to the child.
In particular, Ibuprofen refers to categories B (in the first and the second trimesters), and D in the third trimester.
Category B means that tests have been carried out on animals and have not determined the negative effect on the fetus. At the same time, similar studies involving pregnant women were not carried out. Category D means that scientists have received evidence of the risk of a negative effect of the active substance on the baby in the womb. However, if the possible benefit for the mother exceeds the risk to the child, then Ibuprofen use is justified.
Ibuprofen Pregnancy: Is It Safe?
Continuous use of the drug is contraindicated in the 1st and the 3rd trimesters of pregnancy, as there is a possibility of miscarriage, development of congenital and gene mutations. The active substance of the drug penetrates to the fetus, which can cause the development of a large number of various congenital pathologies. The following complications are possible:
- increased uterine contractility;
- the beginning of premature birth, accompanied by serious complications.
Moreover, long-term use of Ibuprofen during pregnancy can provoke an exacerbation of previously treated gastritis, stomach and duodenal ulcers. In the most severe cases, gastrointestinal bleeding can begin.
Regular intake of Ibuprofen may be prescribed during the 2nd trimester of pregnancy to eliminate severe pain syndrome and normalize body temperature. But all actions must be discussed with the doctor. Otherwise, there is a risk of serious harm to the fetus.
One-time intake of Ibuprofen during pregnancy is not dangerous. That’s why it may be used to relieve acute pain or a rapid drop in temperature.
In general, Ibuprofen is one of the safest antipyretic agents permitted during the gestation of a child. But keep in mind that Ibuprofen during pregnancy is suitable only for a short-term use, not a regular treatment.
The risk of a single use of Ibuprofen in pregnancy tends to zero. That’s why it is used for relief of acute pain or fever. However, even in this case, before using ibuprofen, consult a doctor. The drug may be contraindicated to you for other reasons.
Harmful Effect of Ibuprofen at Later Stages of Pregnancy
Ibuprofen at later stages of pregnancy is used with caution because it suppresses the production of prostaglandins. Thus, it affects uterine contractility and cervical ripening, as well as a generic dominant. As a result, it can cause both premature birth, and with a greater degree of likelihood – prolonged pregnancy, and of course, anomalies of labor. What’s more, Ibuprofen pregnancy has a negative impact on the mother’s coagulation system and an increased risk of bleeding.
In the first two trimesters, ibuprofen during pregnancy can be used if the risk of its use is less than the danger of the disease itself. Still, in the first trimester the risk of taking Ibuprofen is high, as the child’s organs and systems are being formed at this time.
Ibuprofen is used in various forms – from pills to ointments. But keep in mind that contraindications to the use apply to the drug, and not to the form of its release. So Ibuprofen ointment during pregnancy in the third trimester is also prohibited, so as syrups and pills.
The use of this drug for a fairly long period of time is strictly prohibited, because side effects are possible. But in some cases, even a single reception can provoke the appearance of side effects, after the development of which the drug intake is canceled.
Ibuprofen Side Effects Include:
- the occurrence of an allergic reaction;
- disruption of the functioning of the digestive system – vomiting, nausea, problems with stool.
In some cases, as a result of taking this medication, there is a severe headache, which lasts for a long time. There can be a violation of sleep, and a chance of impaired kidney function.
The likelihood that Ibuprofen will cause side effects is the highest in the 3rd trimester of pregnancy.
Ibuprofen Pregnancy: Possible Danger to the Fetus
Characterizing Ibuprofen and pregnancy, it is impossible not to mention the degree of danger of its main substance for the developing and already practically developed fetus. Probably, this is one of the few drugs, special attention and prohibition on the use of which falls not at the early stages of pregnancy (although it is still undesirable to take it), but at the third trimester.
Ibuprofen is able to block hormones responsible for the activity of delivery, and lead to prolonged pregnancy or prolonged labor.
The use of the drug can cause the closure of the arterial duct and trigger the development of pulmonary hypertension in the fetus. What’s more, Ibuprofen pregnancy can cause serious anomalies in the development of the fetus or its death.